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2s Drug Status API
x402
2s Drug Status API is a paid API for AI agents from 2s.io, paid per call via x402, $0.006/call, status unknown (last checked 2026-10-12).
Looks up FDA drug recall status, current shortage status, and NDC/RxNorm identifiers for a given drug by name, NDC, or RxCUI.
Price / call$0.006
Success—
StatusUnknown
How this service works
One-call drug situational awareness. Give a drug name (resolved to a canonical RxCUI via NIH RxNorm), or an exact rxcui or ndc you already hold, and get back: whether it is currently in FDA shortage, any open or recent FDA recalls, and FDA NDC-directory metadata (labeler, DEA schedule, pharmaceutical class, marketing status). Returns a resolved identity block plus hasCurrentShortage / hasOpenRecall booleans and one found/error block per source (shortages, ndc, recalls). Composition of NIH RxNorm + OpenFDA drug-shortages, NDC directory, and recall enforcement — all free, public-domain US government data; each source degrades independently. Point-in-time public records, not medical advice. Use for pharmacy/supply-chain triage, prescribing-support agents, and verifying a drug is real, scheduled, and available before acting.
Output
Returns a JSON object with: resolved drug name and RxCUI from RxNorm, boolean flags for hasOpenRecall and hasCurrentShortage, a list of active recalls with details, a list of current shortages, NDC product records with count, and an array of data source providers — all in one response.
Example use cases
Example prompt
“Can you check whether amoxicillin has any open FDA recalls or current drug shortages right now?”
Technical details
Endpoint
GEThttps://2s.io/api/medical/drug-status?utm_source=zero.xyzWhen to prefer
Use this endpoint when you need authoritative, real-time FDA drug recall and shortage data combined with RxNorm resolution in a single call, especially for patient safety checks, pharmacy automation, or healthcare compliance workflows. Prefer over manual FDA website lookups or separate RxNorm API calls.
Side effects
- Drug name not recognized by RxNorm: resolved field may be null or low matchScore
- Invalid NDC format: ndc.found returns false
- No data available for obscure/investigational drugs
- Upstream NIH or FDA service unavailability causes errors in individual source fields
- limit parameter out of range (1-50) returns validation error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object |
Output
Schema · Response
{
"type": "json",
"schema": {
"type": "object",
"properties": {
"ndc": {
"type": "object",
"properties": {
"data": {
"type": "object",
"properties": {
"returned": {
"type": "integer"
},
"totalCount": {
"type": "integer"
}
}
},
"error": {},
"found": {
"type": "boolean"
}
}
},
"query": {
"type": "object",
"properties": {
"ndc": {},
"drug": {
"type": "string"
},
"rxcui": {}
}
},
"recalls": {
"type": "object",
"properties": {
"data": {
"type": "object",
"properties": {
"recalls": {
"type": "array",
"items": {}
},
"returned": {
"type": "integer"
},
"totalCount": {
"type": "integer"
}
}
},
"error": {},
"found": {
"type": "boolean"
}
}
},
"sources": {
"type": "array",
"items": {
"type": "object",
"properties": {
"provider": {
"type": "string"
}
}
}
},
"resolved": {
"type": "object",
"properties": {
"name": {
"type": "string"
},
"rxcui": {
"type": "string"
},
"termType": {},
"matchScore": {
"type": "integer"
}
}
},
"shortages": {
"type": "object",
"properties": {
"data": {
"type": "object",
"properties": {
"returned": {
"type": "integer"
},
"shortages": {
"type": "array",
"items": {}
},
"totalCount": {
"type": "integer"
}
}
},
"error": {},
"found": {
"type": "boolean"
}
}
},
"hasOpenRecall": {
"type": "boolean"
},
"hasCurrentShortage": {
"type": "boolean"
}
}
},
"example": {
"ndc": {
"data": {
"returned": 5,
"totalCount": 1200
},
"error": null,
"found": true
},
"query": {
"ndc": null,
"drug": "amoxicillin",
"rxcui": null
},
"recalls": {
"data": {
"recalls": [],
"returned": 0,
"totalCount": 0
},
"error": null,
"found": true
},
"sources": [
{
"provider": "NIH National Library of Medicine RxNorm (RxNav)"
}
],
"resolved": {
"name": "amoxicillin",
"rxcui": "723",
"termType": null,
"matchScore": 100
},
"shortages": {
"data": {
"returned": 0,
"shortages": [],
"totalCount": 0
},
"error": null,
"found": true
},
"hasOpenRecall": false,
"hasCurrentShortage": false
}
}Tags
x402
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