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AlphaFold Predicted Protein Structure Lookup
x402
AlphaFold Predicted Protein Structure Lookup is a paid API for AI agents from saylorinnovations.com, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-01).
Retrieves AlphaFold-predicted 3D protein structure data for a given UniProt accession or gene symbol, including model metadata, pLDDT confidence scores, and download links for PDB/mmCIF/PAE files.
Price / call$0.002
Success—
StatusUnknown
How this service works
AlphaFold Predicted Protein Structure. AlphaFold predicted protein structure for a UniProt accession or gene symbol: model id and version, mean pLDDT confidence, fraction of residues per confidence band with an interpretation, and download links (PDB, mmCIF, predicted aligned error). AlphaFold DB (EMBL-EBI / Google DeepMind), CC BY 4.0.
Output
Returns the AlphaFold model ID and version, the mean pLDDT confidence score (0–100), a breakdown of the fraction of residues in each confidence band (very high, confident, low, very low) with interpretations, and direct download URLs for the predicted structure in PDB format, mmCIF format, and the predicted aligned error (PAE) JSON file.
Example use cases
Confidence check for drug target protein
“I'm evaluating TP53 as a drug target — can you fetch the AlphaFold structure for it and tell me the mean pLDDT score and what fraction of residues fall into the high-confidence band?”
Downloading structure files for molecular docking
“I need the AlphaFold PDB and mmCIF download links for the protein with UniProt accession Q9Y261 so I can use them in a docking simulation.”
Comparing model quality across proteins
“Can you get the AlphaFold model version and overall confidence score for BRCA2 so I can compare it to another structure I already have?”
Technical details
Endpoint
GEThttps://saylorinnovations.com/api/bio/alphafold/:id?utm_source=zero.xyzWhen to prefer
Use this endpoint when you need programmatic access to AlphaFold structural predictions and confidence metrics for a specific protein, identified by UniProt accession or gene symbol, without needing to interact with the full AlphaFold DB web interface. Prefer this over manual EBI lookups when building automated pipelines that need pLDDT scores, confidence band breakdowns, and structure download links in a single call.
Side effects
- Unknown UniProt accession or gene symbol returns a 404 or empty result
- Gene symbols with multiple mappings may return unexpected isoform structures
- AlphaFold DB upstream unavailability may cause timeout or error
- Proteins with no AlphaFold prediction (e.g. very large or novel proteins) return no data
- Malformed accession format may return a validation error
Tags
x402
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