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RCSB PDB Protein Structure Search
x402
RCSB PDB Protein Structure Search is a paid API for AI agents from saylorinnovations.com, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-01).
Searches the RCSB Protein Data Bank by free text query and returns total match count plus top structure entries with title, experimental method, resolution, and release date
Price / call$0.002
Success—
StatusUnknown
How this service works
Protein Structure Search (RCSB PDB). Search the Protein Data Bank for 3D structures by free text (protein, organism, ligand, disease): total matches plus the top entries with title, method, resolution and release date, each linking to the full structure record. RCSB PDB, CC0.
Output
Returns a JSON object indicating whether results were found, the total number of matching PDB entries, and an array of top structure records each containing the structure title, experimental determination method (e.g. X-ray crystallography, cryo-EM), resolution in ångströms, release date, and a link to the full RCSB PDB record page.
Example use cases
Drug target structure discovery
“Search the Protein Data Bank for structures of 'HIV protease' — I need the top results showing experimental method and resolution so I can pick the best structure for molecular docking.”
Disease-related protein lookup
“Can you search PDB for protein structures related to Alzheimer's disease and list the top entries with their titles, how they were solved, and when they were published?”
Enzyme structure research
“Look up 3D structures of 'cytochrome P450' in the Protein Data Bank and tell me how many total matches there are plus the details on the top hits including resolution and release date.”
Technical details
Endpoint
GEThttps://saylorinnovations.com/api/bio/pdb-search?utm_source=zero.xyzWhen to prefer
Choose this endpoint when an agent needs to discover experimentally determined 3D protein structures by name, organism, ligand, or disease keyword. It is ideal for bioinformatics research workflows, drug discovery pipelines, or any task requiring structured metadata about PDB entries without needing to download raw structure files. Prefer over manual PDB.org browsing when programmatic, agent-accessible lookup with per-query micropayment billing is acceptable.
Side effects
- Empty query string returns no results or error
- Very broad queries may return thousands of matches but only surface top entries
- Typos or non-standard nomenclature may reduce result count
- PDB service unavailability causes upstream fetch failure
- Rate limiting or payment failure results in HTTP 402 response
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| inputrequired | object | |
| output | object |
Tags
x402
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