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NCBI ClinVar Variant Search via E-utilities
x402
NCBI ClinVar Variant Search via E-utilities is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-15).
Searches NCBI ClinVar database for clinical genetic variants matching a query and returns matching UIDs via E-utilities esearch.
Price / call$0.02
Success—
StatusUnknown
How this service works
Search NCBI ClinVar clinical variants and return matching UIDs for query {q} via E-utilities. Query: ?q= Returns JSON.
Output
A JSON response containing matching ClinVar UIDs (record identifiers) for the given query, along with metadata such as the total count of results, returned from NCBI E-utilities esearch endpoint.
Example use cases
Example prompt
“Can you search ClinVar for pathogenic variants associated with BRCA2 and give me the matching UIDs?”
Technical details
Endpoint
POSThttps://clonecho.builda.company/x402/s/ncbi-esearch-clinvarWhen to prefer
Use this endpoint when you need to programmatically search NCBI ClinVar for clinical variant records and retrieve their UIDs, especially as the first step in a pipeline to fetch full variant details via NCBI E-utilities. Prefer this over manual ClinVar web searches when integrating genomic/clinical data lookups into automated workflows.
Side effects
- Empty result set if query matches no ClinVar records
- Malformed or missing q parameter returns error
- NCBI E-utilities rate limiting or temporary unavailability
- Very broad queries may return truncated or paginated UID lists
- Special characters in query string may need URL encoding
Tags
x402
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