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Compound Target & Mechanism of Action Lookup
x402
Compound Target & Mechanism of Action Lookup is a paid API for AI agents from win.oneshotagent.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-10-25).
Given a drug or compound name or ChEMBL ID, returns its protein targets, mechanisms of action, action types, and supporting biomedical references.
Price / call$0.005
Success—
StatusUnknown
How this service works
Find a compound’s protein targets and mechanisms of action, with supporting references.
Output
Returns a JSON object with the matched compound's canonical name, ChEMBL ID, drug type, mechanisms of action (each with target gene symbols, Ensembl gene IDs, target name, action type, and DailyMed or other reference URLs), a list of all action types, target types, and the maximum clinical stage reached (e.g. APPROVAL).
Example use cases
Drug repurposing target analysis
“I'm researching whether metformin could be repurposed for cancer treatment — can you look up all its known protein targets and mechanisms of action, including the gene symbols and action types?”
Biomedical literature enrichment
“For the compound with ChEMBL ID CHEMBL25, what are the molecular targets and mechanisms of action? I need the target gene symbols, action types, and reference URLs so I can cite them.”
Competitive drug landscape research
“Can you find the protein targets and mechanism of action for pembrolizumab, including what clinical stage it has reached and whether it's been approved?”
Technical details
Endpoint
POSThttps://win.oneshotagent.com/v1/tools/lookup/compound-targets?utm_source=zero.xyzWhen to prefer
Choose this endpoint when you need structured, reference-backed protein target and mechanism-of-action data for a specific drug or compound, especially when you have a compound name or ChEMBL ID and need downstream pharmacological analysis. Prefer it over general web search when you need machine-readable output with gene symbols and citations rather than prose descriptions.
Side effects
- Compound name not found in ChEMBL — matched:false with empty mechanisms array
- Ambiguous compound name resolves to unintended first search hit
- ChEMBL ID format invalid — rejected before lookup
- No mechanism data available for a known compound — empty mechanisms array
- Rate limiting or payment failure due to x402 protocol issues
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| name | string | Drug or compound name; the first search hit is used. 2 to 100 characters. |
| chembl_id | string | ChEMBL molecule identifier; lowercase is accepted. CHEMBL followed by 1 to 9 digits, without a leading zero. |
Output
Schema · Response
{
"type": "json",
"example": {
"name": "ADALIMUMAB",
"matched": true,
"chembl_id": "CHEMBL1201580",
"drug_type": "Antibody",
"candidates": [],
"mechanisms": [
{
"targets": [
{
"symbol": "TNF",
"ensembl_gene_id": "ENSG00000232810"
}
],
"mechanism": "TNF-alpha inhibitor",
"references": [
{
"urls": [
"http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=608d4f0d-b19f-46d3-749a-7159aa5f933d"
],
"source": "DailyMed"
}
],
"action_type": "INHIBITOR",
"target_name": "Tumor necrosis factor"
}
],
"action_types": [
"INHIBITOR"
],
"target_types": [
"single protein"
],
"max_clinical_stage": "APPROVAL"
}
}Tags
x402
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