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Protein Function Lookup by UniProt Accession
x402
Protein Function Lookup by UniProt Accession is a paid API for AI agents from win.oneshotagent.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-10-29).
Retrieves a protein's function, literature citations, organism, cellular locations, and catalytic activities given a UniProt accession identifier.
Price / call$0.005
Success—
StatusUnknown
How this service works
Look up a protein’s function, literature citations, organism, cellular locations and catalytic activities by accession.
Output
Returns structured data for the specified protein including its functional description, organism of origin, subcellular/cellular locations, catalytic activities, literature citation references, and optionally the full amino-acid sequence.
Example use cases
Drug target characterization
“What is the biological function, subcellular location, and catalytic activity of the protein with UniProt accession P00533? I'm evaluating it as a drug target.”
Literature review for a protein
“Can you pull all the literature citations and functional annotations for UniProt accession O60341 so I can start a literature review?”
Enzyme activity identification
“I need to know the catalytic activities and the organism source for UniProt accession P12931 — and please include the amino-acid sequence as well.”
Technical details
Endpoint
POSThttps://win.oneshotagent.com/v1/tools/lookup/protein-function?utm_source=zero.xyzWhen to prefer
Use this endpoint when you need structured, curated protein annotations (function, localization, catalytic activity, citations) for a known UniProt accession. It is ideal for bioinformatics pipelines, drug target research, or any automated workflow that requires reliable, machine-readable protein metadata without scraping UniProt directly.
Side effects
- Invalid or non-existent UniProt accession returns an error or empty result
- Accession for a protein not yet annotated in UniProt may return partial data
- Network timeouts if UniProt upstream is slow
- Malformed accession string (wrong format) may return a validation error
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| accession | string | The UniProt accession identifying the protein, for example P04637 |
| include_sequence | boolean | Include the amino-acid sequence. Defaults to `false`. |
Output
Schema · Response
{
"type": "json",
"example": {
"protein": null,
"inactive_reason": {
"reason_type": "DEMERGED",
"replacement_accessions": [
"P68251",
"P68250"
]
}
}
}Tags
x402
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