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UniProt Protein Sequence Lookup
x402
UniProt Protein Sequence Lookup is a paid API for AI agents from win.oneshotagent.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-10-29).
Retrieves the reference amino-acid sequence of a protein or isoform by UniProt accession, including sequence length, molecular weight, checksums, and isoform list.
Price / call$0.005
Success—
StatusUnknown
How this service works
Get the reference amino-acid sequence of a protein or an isoform by UniProt accession, with its length, weight, checksums and isoforms.
Output
Returns the full reference amino acid sequence for the requested protein or isoform, along with the sequence length, molecular weight, CRC64 and MD5 checksums, and a list of available isoforms associated with the UniProt accession.
Example use cases
Validate protein identity by sequence
“I need to confirm the canonical amino acid sequence for the BRCA1 protein — can you pull it up using its UniProt accession P38398 and give me the sequence, its length, and any known isoforms?”
Retrieve isoform sequence for analysis
“Can you fetch the sequence for isoform 2 of the human insulin receptor, UniProt accession P06213-2, including its molecular weight and checksum?”
Gather protein metadata for a pipeline
“I'm building a bioinformatics pipeline and need the reference sequence, length, and molecular weight for the protein with UniProt accession Q9Y6K9 — can you get that for me?”
Technical details
Endpoint
POSThttps://win.oneshotagent.com/v1/tools/lookup/protein-sequence?utm_source=zero.xyzWhen to prefer
Choose this endpoint when you need structured protein sequence data — including isoforms, weight, and checksums — directly from UniProt without setting up your own UniProt API integration. Ideal for AI agents that need to programmatically retrieve protein metadata as part of a bioinformatics workflow, drug discovery pipeline, or sequence validation task, especially when pay-per-call pricing is preferable to managing API keys.
Side effects
- Invalid or non-existent UniProt accession returns an error or empty result
- Malformed accession format (e.g. missing dash for isoform) causes a validation error
- Network or service timeout for large proteins
- Payment failure if x402 micropayment is not processed correctly
Input
Schema · Request body
| Field | Type | Description |
|---|---|---|
| accession | string | The UniProt accession, for example P04637, or an isoform accession, for example P04637-2 |
Output
Schema · Response
{
"type": "json",
"example": {
"protein": null,
"inactive": {
"reason": "demerged",
"replaced_by": [
"P99999",
"P99998"
]
}
}
}Tags
x402
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